Baker Bros. Advisors

Superinvestor profile · Rank #22 by reported 13F value (2026 Q2 filers) · CIK 0001263508 · All profiles
Founded 2000New York, New York, USConcentrated long-term biotechnology and healthcare equity investingKey person: Julian Baker and Felix Baker
Reported 13F value
$20.0B
Period 2026-06-30 · Filed 2026-08-14
Positions
84
Top 10 = 72.8% of value
Clone performance
Withheld
Price coverage too low — see note
Latest-quarter activity
8 new · 8 exited
16 increased · 7 decreased
Clone performance withheld for this manager. Only 75.3% of the latest filing's reported value sits inside our price history, and on average 51% of each historical segment's weight is unpriced as well; the rest is mostly non-U.S. listings and small-cap names we cannot price reliably. A clone computed from the priced minority would misrepresent the disclosed portfolio, so we do not publish one. The snapshot, holdings and filing history below are complete as reported. Evidence: filing-by-filing dossier (PDF) · Methodology (PDF)

Top holdings — 2026 Q2 filing

TickerCompanyWeightReported value
INCYIncyte Corporation17.48%$3.5B
ONCBeone Medicines Ltd.12.57%$2.5B
RVMDRevolution Medicines, Inc.10.74%$2.1B
MDGLMadrigal Pharmaceuticals, Inc.5.77%$1.2B
ACADAcadia Pharmaceuticals Inc.5.44%$1.1B
KYMRKymera Therapeutics, Inc.4.97%$993M
INSMInsmed Incorporated4.70%$938M
CELCCelcuity Inc.4.15%$828M
KODKodiak Sciences Inc.3.89%$776M
RYTMRhythm Pharmaceuticals, Inc.3.12%$622M

As reported on the 2026-06-30 Form 13F (filed 2026-08-14). Full holdings and quarter changes: holdings page.

Filing history in this profile

Every clone input traces to one of these SEC filings. 75.3% of the latest filing's reported value is covered by our price history; the remainder is mostly non-U.S. listings, recent IPOs or delisted names and is excluded from the clone.

QuarterSEC accession no.FiledDisclosed CUSIPs
2026Q20001104659-26-0971912026-08-1483
2026Q10001104659-26-0625472026-05-1584
2025Q40001104659-26-0163742026-02-1785
2025Q30001104659-25-1125952025-11-1490
2025Q20001104659-25-0785732025-08-1489
2025Q10001104659-25-0495182025-05-1588
2024Q40001104659-25-0140852025-02-1493
2024Q30001104659-24-1188992024-11-1492
2024Q20001104659-24-0896062024-08-1493
2024Q10001104659-24-0619962024-05-1587
2023Q40001104659-24-0240532024-02-1482
2023Q30001104659-23-1181572023-11-1499
2023Q20001104659-23-0913432023-08-14106
2023Q10001104659-23-0607202023-05-15105
2022Q40001104659-23-0215512023-02-14111
2022Q30001104659-22-1185272022-11-14113
2022Q20001104659-22-0912862022-08-15114
2022Q10001104659-22-0612882022-05-16115
2021Q40001104659-22-0227252022-02-14116
2021Q30001104659-21-1391092021-11-15116
2021Q20001104659-21-1063142021-08-16114
2021Q10001104659-21-0680252021-05-17123
2020Q40001104659-21-0238332021-02-16124
2020Q30001104659-20-1257672020-11-16117
2020Q20001104659-20-0955182020-08-14112
2020Q10001104659-20-0625752020-05-15108
2019Q40001104659-20-0218382020-02-1497
2019Q30001104659-19-0641692019-11-14107
2019Q20001144204-19-0400332019-08-14101
2019Q10001144204-19-0265552019-05-1594
2018Q40001144204-19-0071562019-02-1391
2018Q30001144204-18-0598912018-11-1497
2018Q20001144204-18-0446072018-08-14113
2018Q10001144204-18-0288182018-05-15108
2017Q40001144204-18-0088392018-02-14116
2017Q30001144204-17-0589632017-11-14113
2017Q20001144204-17-0430862017-08-14113
2017Q10001144204-17-0274302017-05-15111
2016Q40001144204-17-0088362017-02-14124
2016Q30001144204-16-1343522016-11-14124

Background (founded / HQ / style) source: https://www.insidermonkey.com/hedge-fund/baker+bros+advisors/320 — Healthcare-focused hedge fund founded by brothers Julian and Felix Baker; known for concentrated, long-horizon biotech positions.