Fund · 13F portfolio

Paradigm Biocapital Advisors

Paradigm Biocapital Advisors · 2026 Q2 13F · period ended Jun 30, 2026 · filed Aug 14, 2026
Reported value
$5.3B
2026 Q2 filing
Stocks held
26
as of Jun 30, 2026
Opened / added
7 / 10
vs previous quarter
Trimmed / exited
7 / 11
vs previous quarter

Holdings · 2026 Q2

TickerCompanyWeightSharesChange
RVMDREVOLUTION MEDICINES INC22.31%6,361,323TRIMMED (-4.4%)
EWTXEdgewise Therapeutics, Inc.7.77%10,215,455ADDED (+38.7%)
GMABGENMAB A/S6.76%13,133,131ADDED (+64.8%)
SYRESPYRE THERAPEUTICS INC6.38%3,840,778ADDED (+96.2%)
ORKAOruka Therapeutics, Inc.3.82%2,144,526TRIMMED (-7.6%)
TNGXTANGO THERAPEUTICS INC3.72%6,357,523ADDED (+58.6%)
BLTEBELITE BIO, INC3.55%1,232,877ADDED (+10.6%)
ERASERASCA INC3.28%9,550,000TRIMMED (-8.1%)
TARSTARSUS PHARMACEUTICALS INC3.27%2,775,649ADDED (+8.3%)
ALNYALNYLAM PHARMACEUTICALS, INC.2.71%480,000NEW
INSMINSMED Inc2.65%1,325,977ADDED (+5.7%)
MBXMBX BIOSCIENCES INC2.59%2,508,015NEW
PCVXVaxcyte, Inc.2.32%2,127,852TRIMMED (-55.6%)
VRDNViridian Therapeutics, Inc.\DE2.31%6,723,788ADDED (+113.5%)
OLMAOlema Pharmaceuticals, Inc.2.03%8,670,576ADDED (+8.1%)
JBIOJADE BIOSCIENCES INC1.19%2,857,405NEW
TYRATYRA BIOSCIENCES INC1.09%1,828,607TRIMMED (-11.0%)
ASMBASSEMBLY BIOSCIENCES INC0.80%1,553,748ADDED (+133.6%)
EYPTEYEPOINT INC0.77%2,890,397TRIMMED (-8.0%)
ACHVACHIEVE LIFE SCIENCES INC0.61%4,951,856NEW
VORVOR BIOPHARMA INC0.60%1,750,000HELD
MPLTMAPLIGHT THERAPEUTICS INC0.46%685,852NEW
KARDKARDIGAN INC0.40%900,000NEW
LXEOLEXEO THERAPEUTICS INC0.36%4,175,382TRIMMED (-32.5%)
EDITEDITAS MEDICINE INC0.34%5,586,625NEW
IVAINVENTIVA SA - ADR0.28%4,000,000HELD

The weights above sum to 82.4% of the fund’s reported 13F value. Only positions matched to a U.S.-listed ticker are listed; the remainder sits in unmatched or non-equity positions in the filing.

Exited this quarter: ABVX, BBOT, CYTK, GPCR, KLRS, MANE, MAZE, MIRM, ORIC, SRRK, URGN.

Source: SEC Form 13F filing for the quarter ended Jun 30, 2026, filed Aug 14, 2026. CIK 0001855655. Change labels compare with the fund’s previous quarterly filing. 13F filings cover long positions only.

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