Perceptive Advisors

Superinvestor profile · Rank #70 by reported 13F value (2026 Q2 filers) · CIK 0001224962 · All profiles
Founded 1999New York City, New York, USHealthcare and biotechnology focused investing across hedge fund, venture capital, private equity and private creditKey person: Joseph Edelman
Reported 13F value
$6.7B
Period 2026-06-30 · Filed 2026-08-14
Positions
109
Top 10 = 47.3% of value
Clone performance
Withheld
Price coverage too low — see note
Latest-quarter activity
29 new · 14 exited
30 increased · 26 decreased
Clone performance withheld for this manager. Only 80.6% of the latest filing's reported value sits inside our price history, and on average 70% of each historical segment's weight is unpriced as well; the rest is mostly non-U.S. listings and small-cap names we cannot price reliably. A clone computed from the priced minority would misrepresent the disclosed portfolio, so we do not publish one. The snapshot, holdings and filing history below are complete as reported. Evidence: filing-by-filing dossier (PDF) · Methodology (PDF)

Top holdings — 2026 Q2 filing

TickerCompanyWeightReported value
PRAXPraxis Precision Medicines I10.23%$682M
SYRESpyre Therapeutics Inc5.76%$383M
CELCCelcuity Inc5.02%$334M
ASNDAscendis Pharma A/S4.66%$310M
RYTMRhythm Pharmaceuticals Inc4.31%$287M
ROIVRoivant Sciences Ltd4.30%$286M
RLAYRelay Therapeutics Inc3.96%$264M
TVTXTravere Therapeutics Inc3.20%$213M
KARDKardigan Inc2.94%$196M
Nuvalent Inc2.93%$195M

As reported on the 2026-06-30 Form 13F (filed 2026-08-14). Full holdings and quarter changes: holdings page.

Filing history in this profile

Every clone input traces to one of these SEC filings. 80.6% of the latest filing's reported value is covered by our price history; the remainder is mostly non-U.S. listings, recent IPOs or delisted names and is excluded from the clone.

QuarterSEC accession no.FiledDisclosed CUSIPs
2026Q20001012975-26-0007772026-08-14101
2026Q10001012975-26-0004992026-05-2991
2025Q40001012975-26-0001552026-02-17111
2025Q30001012975-25-0007622025-11-1490
2025Q20001012975-25-0004462025-08-1482
2025Q10001012975-25-0002422025-05-1586
2024Q40001012975-25-0000902025-02-1497
2024Q30001012975-24-0004882024-11-14102
2024Q20001012975-24-0003462024-08-16107
2024Q10001012975-24-0002182024-05-15105
2023Q40001012975-24-0001122024-02-2697
2023Q30001012975-23-0004712023-11-1487
2023Q20001012975-23-0003652023-08-2488
2023Q10001012975-23-0002422023-05-1698
2022Q40001012975-23-0000992023-02-1494
2022Q30001012975-22-0005022022-11-14113
2022Q20001012975-22-0003652022-08-15107
2022Q10001012975-22-0002412022-05-16131
2021Q40001012975-22-0000812022-02-14138
2021Q30001012975-21-0004922021-12-03133
2021Q20001012975-21-0003262021-08-17143
2021Q10001012975-21-0002422021-06-10133
2020Q40001012975-21-0000862021-02-16134
2020Q30001012975-20-0008352020-11-16119
2020Q20001012975-20-0007012020-08-17119
2020Q10001012975-20-0004722020-05-18109
2019Q40001012975-20-0002502020-02-19110
2019Q30001012975-19-0007072019-11-14103
2019Q20001012975-19-0005832019-08-14100
2019Q10001012975-19-0003802019-05-1695
2018Q40001012975-19-0001772019-02-1496
2018Q30001012975-18-0012392018-11-14112
2018Q20001012975-18-0010302018-08-14120
2018Q10001012975-18-0004252018-05-15126
2017Q40001012975-18-0001712018-02-14127
2017Q30001012975-17-0008462017-11-14129
2017Q20001012975-17-0006242017-08-14118
2017Q10001019056-17-0004672017-05-15166
2016Q40001019056-17-0003092017-03-20183
2016Q30001019056-16-0016482016-11-14186

Background (founded / HQ / style) source: https://en.wikipedia.org/wiki/Perceptive_Advisors — Founded in July 1999 by Joseph Edelman, who serves as CEO.