Reported value
$6.7B
2026 Q2 filing
| Ticker | Company | Weight | Shares | Change |
|---|---|---|---|---|
| PRAX | Praxis Precision Medicines, Inc. | 10.23% | 2,035,986 | HELD |
| SYRE | SPYRE THERAPEUTICS INC | 5.76% | 4,319,496 | ADDED (+14.2%) |
| CELC | Celcuity Inc. | 5.02% | 3,197,200 | ADDED (+2.2%) |
| ASND | Ascendis Pharma A/S | 4.66% | 1,163,721 | NEW |
| RYTM | RHYTHM PHARMACEUTICALS INC | 4.31% | 2,586,295 | ADDED (+9.0%) |
| ROIV | Roivant Sciences Ltd. | 4.30% | 8,085,461 | TRIMMED (-2.4%) |
| RLAY | Relay Therapeutics, Inc. | 3.96% | 14,106,187 | ADDED (+44.7%) |
| TVTX | Travere Therapeutics, Inc. | 3.20% | 3,752,574 | TRIMMED (-9.4%) |
| KARD | KARDIGAN INC | 2.94% | 8,200,662 | NEW |
| EWTX | Edgewise Therapeutics, Inc. | 2.67% | 4,373,974 | TRIMMED (-1.1%) |
| AMLX | Amylyx Pharmaceuticals, Inc. | 2.25% | 8,334,882 | ADDED (+0.6%) |
| ORKA | Oruka Therapeutics, Inc. | 1.92% | 1,345,063 | TRIMMED (-3.6%) |
| INBX | Inhibrx Biosciences, Inc. | 1.85% | 1,297,763 | TRIMMED (-10.0%) |
| PTGX | Protagonist Therapeutics, Inc | 1.81% | 981,879 | TRIMMED (-20.2%) |
| SLDB | SOLID BIOSCIENCES INC | 1.79% | 11,906,646 | HELD |
| ZYME | ZYMEWORKS INC | 1.64% | 4,182,953 | ADDED (+19.2%) |
| TNGX | TANGO THERAPEUTICS INC | 1.58% | 3,377,000 | ADDED (+317.9%) |
| IMTX | Immatics N.V. | 1.58% | 10,383,456 | HELD |
| NRIX | NURIX THERAPEUTICS INC | 1.57% | 4,320,422 | ADDED (+16.4%) |
| BCRX | BIOCRYST PHARMACEUTICALS INC | 1.55% | 10,308,888 | ADDED (+38.7%) |
| RVMD | REVOLUTION MEDICINES INC | 1.48% | 527,600 | ADDED (+104.0%) |
| AVLN | AVALYN PHARMA INC | 1.32% | 2,675,296 | NEW |
| DYN | DYNE THERAPEUTICS INC | 0.90% | 2,689,235 | TRIMMED (-42.4%) |
| BIIB | BIOGEN INC. | 0.90% | 276,173 | NEW |
| IMVT | Immunovant, Inc. | 0.79% | 1,357,383 | TRIMMED (-15.0%) |
| UNH | UNITEDHEALTH GROUP INC | 0.73% | 116,806 | NEW |
| IONS | IONIS PHARMACEUTICALS INC | 0.67% | 566,000 | ADDED (+12.3%) |
| STRO | SUTRO BIOPHARMA INC | 0.65% | 1,304,846 | ADDED (+82.4%) |
| ANRO | Alto Neuroscience, Inc. | 0.64% | 1,609,893 | TRIMMED (-19.9%) |
| JAZZ | Jazz Pharmaceuticals plc | 0.61% | 170,000 | HELD |
| CRVS | CORVUS PHARMACEUTICALS INC | 0.60% | 2,667,441 | ADDED (+16.4%) |
| SION | Sionna Therapeutics, Inc. | 0.60% | 905,000 | ADDED (+37.4%) |
| CTMX | CYTOMX THERAPEUTICS INC | 0.59% | 10,439,185 | ADDED (+3.4%) |
| AORT | ARTIVION, INC. | 0.59% | 1,737,290 | ADDED (+6.1%) |
| XFOR | X4 PHARMACEUTICALS INC | 0.56% | 7,933,491 | ADDED (+17.7%) |
| CORT | CORCEPT THERAPEUTICS INC | 0.52% | 398,385 | ADDED (+696.8%) |
| RGEN | REPLIGEN CORP | 0.51% | 248,212 | TRIMMED (-11.5%) |
| AVR | ANTERIS TECHNOLOGIES GLOBAL | 0.51% | 3,425,476 | HELD |
| RAPP | RAPPORT THERAPEUTICS INC | 0.48% | 773,342 | ADDED (+14.8%) |
| DMRA | Damora Therapeutics, Inc. | 0.48% | 1,223,000 | HELD |
| CRL | CHARLES RIVER LABORATORIES INTERNATIONAL, INC. | 0.48% | 140,000 | NEW |
| AXSM | Axsome Therapeutics, Inc. | 0.44% | 118,450 | TRIMMED (-21.0%) |
| DBVT | DBV TECHNOLOGIES SA-SPON ADR | 0.41% | 1,653,350 | ADDED (+71.4%) |
| IRTC | iRhythm Holdings, Inc. | 0.40% | 223,766 | ADDED (+113.1%) |
| ADPT | Adaptive Biotechnologies Corp | 0.39% | 1,217,325 | ADDED (+698.2%) |
| SABS | SAB BIOTHERAPEUTICS INC | 0.39% | 6,627,501 | ADDED (+3.0%) |
| DHR | DANAHER CORP /DE/ | 0.37% | 130,000 | NEW |
| TENX | TENAX THERAPEUTICS INC | 0.37% | 1,700,000 | ADDED (+17.4%) |
| NAUT | Nautilus Biotechnology, Inc. | 0.33% | 11,634,211 | TRIMMED (-7.6%) |
| OBIO | ORCHESTRA BIOMED HOLDINGS IN | 0.33% | 5,037,906 | HELD |
| ISRG | INTUITIVE SURGICAL INC | 0.31% | 51,884 | TRIMMED (-39.3%) |
| ANL | ADLAI NORTYE GROUP LTD | 0.31% | 1,793,190 | NEW |
| CTNM | CONTINEUM THERAPEUTICS INC-A | 0.31% | 1,255,592 | HELD |
| NVCT | NUVECTIS PHARMA INC | 0.28% | 1,000,000 | NEW |
| PALI | PALISADE BIO INC | 0.26% | 8,425,065 | TRIMMED (-5.6%) |
| OMDA | OMADA HEALTH INC | 0.26% | 786,330 | HELD |
| LONA | LEONABIO INC | 0.26% | 1,859,322 | HELD |
| EOLS | EVOLUS INC | 0.26% | 2,459,285 | ADDED (+91.1%) |
| IVVD | Invivyd, Inc. | 0.24% | 18,490,636 | TRIMMED (-11.4%) |
| MIRM | Mirum Pharmaceuticals, Inc. | 0.20% | 115,391 | NEW |
| SRZN | SURROZEN INC | 0.20% | 503,985 | ADDED (+119.7%) |
| BBNX | Beta Bionics, Inc. | 0.20% | 832,944 | TRIMMED (-1.2%) |
| AXGN | Axogen, Inc. | 0.17% | 247,312 | TRIMMED (-64.5%) |
| OSCR | Oscar Health, Inc. | 0.17% | 400,000 | NEW |
| OCS | Oculis Holding AG | 0.17% | 808,827 | ADDED (+63.8%) |
| SPTX | SEAPORT THERAPEUTICS INC | 0.16% | 500,000 | NEW |
| VRDN | Viridian Therapeutics, Inc.\DE | 0.16% | 581,980 | TRIMMED (-50.3%) |
| BSX | BOSTON SCIENTIFIC CORP | 0.16% | 250,000 | NEW |
| BLLN | BillionToOne, Inc. | 0.16% | 86,812 | TRIMMED (-5.4%) |
| ABVX | Abivax S.A. | 0.15% | 74,000 | TRIMMED (-77.5%) |
| NTRA | Natera, Inc. | 0.14% | 34,689 | NEW |
| ENGN | ENGENE THERAPEUTICS INC | 0.13% | 4,822,169 | NEW |
| RACC | Research Alliance Corp III | 0.12% | 750,000 | NEW |
| AGMB | AGOMAB THERAPEUTICS NV | 0.12% | 600,000 | HELD |
| CGEM | Cullinan Therapeutics, Inc. | 0.12% | 426,478 | NEW |
| QURE | uniQure N.V. | 0.12% | 168,000 | NEW |
| MOBI | MOBIA MEDICAL INC | 0.11% | 523,654 | NEW |
| ADGM | ADAGIO MEDICAL HOLDINGS INC | 0.10% | 9,876,586 | HELD |
| GH | Guardant Health, Inc. | 0.09% | 41,327 | TRIMMED (-86.2%) |
| PHAT | PHATHOM PHARMACEUTICALS INC | 0.09% | 532,000 | TRIMMED (-42.5%) |
| OTLK | OUTLOOK THERAPEUTICS INC | 0.07% | 3,139,216 | NEW |
| COGT | COGENT BIOSCIENCES INC | 0.07% | 121,082 | HELD |
| EDSA | EDESA BIOTECH INC | 0.07% | 563,239 | HELD |
| AVTX | AVALO THERAPEUTICS INC | 0.06% | 219,813 | ADDED (+57.4%) |
| TWST | Twist Bioscience Corp | 0.06% | 36,812 | TRIMMED (-75.5%) |
| CBIO | CRESCENT BIOPHARMA, INC. | 0.06% | 206,942 | HELD |
| XERS | Xeris Biopharma Holdings, Inc. | 0.06% | 467,013 | NEW |
| OM | Outset Medical, Inc. | 0.05% | 833,333 | HELD |
| BDSX | BIODESIX INC | 0.04% | 108,694 | NEW |
| RVMDW | REVOLUTION MEDICINES INC-28 | 0.04% | 250,000 | HELD |
| CNTB | Connect Biopharma Holdings Ltd | 0.03% | 792,696 | HELD |
| KPRX | KIORA PHARMACEUTICALS INC | 0.02% | 438,471 | NEW |
| MDLN | Medline Inc. | 0.02% | 28,000 | HELD |
| ADMA | ADMA BIOLOGICS, INC. | 0.01% | 113,765 | TRIMMED (-75.7%) |
| CPIX | CUMBERLAND PHARMACEUTICALS INC | 0.01% | 96,982 | TRIMMED (-50.8%) |
| XGN | EXAGEN INC. | 0.01% | 114,893 | HELD |
| ENSC | ENSYSCE BIOSCIENCES INC | <0.01% | 86,666 | HELD |
The weights above sum to 88.8% of the fund’s reported 13F value. Only positions matched to a U.S.-listed ticker are listed; the remainder sits in unmatched or non-equity positions in the filing.
Exited this quarter: ASND, BLTE, DRUG, EVMN, IKT, IRD, NBIX, NMRA, OCUL, PTN.
Source: SEC Form 13F filing for the quarter ended Jun 30, 2026, filed Aug 14, 2026. CIK 0001224962. Change labels compare with the fund’s previous quarterly filing. 13F filings cover long positions only.
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