Reported value
$5.4B
2026 Q2 filing
| Ticker | Company | Weight | Shares | Change |
|---|---|---|---|---|
| EWTX | Edgewise Therapeutics, Inc. | 11.68% | 15,518,492 | HELD |
| ELVN | ENLIVEN THERAPEUTICS INC | 6.37% | 6,776,632 | TRIMMED (-14.9%) |
| LLY | ELI LILLY & Co | 5.73% | 257,900 | ADDED (+8.9%) |
| MBX | MBX BIOSCIENCES INC | 3.51% | 3,428,736 | TRIMMED (-5.7%) |
| SVA | SINOVAC BIOTECH LTD | 3.42% | 2,718,735 | HELD |
| AZN | ASTRAZENECA PLC | 3.17% | 915,700 | ADDED (+36.6%) |
| GPCR | STRUCTURE THERAPEUTICS INC | 2.20% | 2,209,400 | ADDED (+49.7%) |
| SION | Sionna Therapeutics, Inc. | 2.08% | 2,555,877 | TRIMMED (-27.6%) |
| CRVS | CORVUS PHARMACEUTICALS INC | 1.98% | 7,165,006 | HELD |
| AVBP | ArriVent BioPharma, Inc. | 1.95% | 3,027,328 | HELD |
| GH | Guardant Health, Inc. | 1.62% | 583,700 | ADDED (+34.1%) |
| ARGX | ARGENX SE - ADR | 1.60% | 92,880 | TRIMMED (-32.2%) |
| MRK | Merck & Co., Inc. | 1.58% | 663,400 | HELD |
| QURE | uniQure N.V. | 1.54% | 1,807,486 | TRIMMED (-15.4%) |
| PRAX | Praxis Precision Medicines, Inc. | 1.43% | 230,100 | ADDED (+33.4%) |
| EW | Edwards Lifesciences Corp | 1.40% | 834,900 | TRIMMED (-32.2%) |
| PRLD | PRELUDE THERAPEUTICS INC | 1.36% | 13,724,571 | ADDED (+25.8%) |
| ABVX | Abivax S.A. | 1.35% | 546,522 | ADDED (+17.4%) |
| DYN | DYNE THERAPEUTICS INC | 1.33% | 3,235,684 | ADDED (+10.9%) |
| NTRA | Natera, Inc. | 1.32% | 262,000 | HELD |
| CGON | CG ONCOLOGY INC | 1.28% | 972,800 | ADDED (+2.6%) |
| UNH | UNITEDHEALTH GROUP INC | 1.24% | 161,100 | NEW |
| SPRY | ARS Pharmaceuticals, Inc. | 1.23% | 8,288,510 | HELD |
| ASND | Ascendis Pharma A/S | 1.21% | 244,456 | NEW |
| HUM | HUMANA INC | 1.21% | 164,100 | NEW |
| COGT | COGENT BIOSCIENCES INC | 1.21% | 1,681,300 | ADDED (+422.0%) |
| BSX | BOSTON SCIENTIFIC CORP | 1.17% | 1,483,200 | TRIMMED (-37.7%) |
| ISRG | INTUITIVE SURGICAL INC | 1.16% | 157,900 | TRIMMED (-24.3%) |
| MLYS | MINERALYS THERAPEUTICS INC | 1.05% | 2,110,300 | ADDED (+2.8%) |
| ODTX | ODYSSEY THERAPEUTICS INC | 1.04% | 3,001,198 | NEW |
| XENE | XENON PHARMACEUTICALS INC | 1.00% | 892,471 | TRIMMED (-15.8%) |
| ARQT | ARCUTIS BIOTHERAPEUTICS INC | 0.99% | 2,042,000 | NEW |
| BMY | BRISTOL MYERS SQUIBB CO | 0.99% | 925,000 | HELD |
| QTTB | Q32 BIO INC | 0.97% | 4,127,987 | ADDED (+83.2%) |
| SYK | STRYKER CORP | 0.93% | 159,100 | TRIMMED (-12.8%) |
| CAI | CARIS LIFE SCIENCES INC | 0.93% | 2,806,811 | HELD |
| TMO | THERMO FISHER SCIENTIFIC INC. | 0.84% | 90,700 | ADDED (+95.1%) |
| PVLA | PALVELLA THERAPEUTICS INC | 0.83% | 292,360 | ADDED (+117.2%) |
| ELV | Elevance Health, Inc. | 0.82% | 114,700 | HELD |
| STTK | SHATTUCK LABS INC | 0.81% | 6,306,127 | HELD |
| UPB | UPSTREAM BIO INC | 0.73% | 5,693,589 | HELD |
| RYTM | RHYTHM PHARMACEUTICALS INC | 0.66% | 322,900 | ADDED (+2.8%) |
| SNDX | Syndax Pharmaceuticals Inc | 0.62% | 1,542,000 | ADDED (+60.2%) |
| CMPX | COMPASS THERAPEUTICS INC | 0.62% | 15,219,994 | HELD |
| NKTR | NEKTAR THERAPEUTICS | 0.60% | 465,346 | ADDED (+69.2%) |
| KRYS | Krystal Biotech, Inc. | 0.57% | 83,200 | ADDED (+20.4%) |
| PRLD | PRELUDE THERAPEUTICS INC | 0.56% | 5,680,186 | TRIMMED (-8.5%) |
| AXSM | Axsome Therapeutics, Inc. | 0.53% | 117,578 | TRIMMED (-45.0%) |
| KNSA | Kiniksa Pharmaceuticals International, plc | 0.50% | 420,600 | ADDED (+132.9%) |
| TRVI | Trevi Therapeutics, Inc. | 0.49% | 1,430,293 | TRIMMED (-41.7%) |
| IRON | DISC MEDICINE INC | 0.48% | 357,535 | TRIMMED (-66.5%) |
| WST | WEST PHARMACEUTICAL SERVICES INC | 0.47% | 70,600 | NEW |
| RLMD | RELMADA THERAPEUTICS INC | 0.47% | 3,631,195 | TRIMMED (-23.0%) |
| URGN | UroGen Pharma Ltd. | 0.46% | 676,187 | TRIMMED (-22.8%) |
| STRO | SUTRO BIOPHARMA INC | 0.46% | 743,944 | TRIMMED (-7.1%) |
| SVRA | SAVARA INC | 0.45% | 3,959,900 | ADDED (+523.6%) |
| NPCE | NEUROPACE INC | 0.44% | 1,505,125 | TRIMMED (-28.2%) |
| AURA | AURA BIOSCIENCES INC | 0.44% | 3,333,333 | NEW |
| ORIC | Oric Pharmaceuticals, Inc. | 0.40% | 2,015,000 | TRIMMED (-25.2%) |
| BCRX | BIOCRYST PHARMACEUTICALS INC | 0.34% | 1,852,000 | ADDED (+29.9%) |
| BIOA | BIOAGE LABS INC | 0.34% | 752,153 | ADDED (+5.7%) |
| LXEO | LEXEO THERAPEUTICS INC | 0.34% | 3,947,850 | ADDED (+9.6%) |
| WHWK | WHITEHAWK THERAPEUTICS INC | 0.33% | 3,934,296 | TRIMMED (-5.6%) |
| DFTX | DEFINIUM THERAPEUTICS INC | 0.32% | 365,400 | TRIMMED (-54.6%) |
| SYRE | SPYRE THERAPEUTICS INC | 0.31% | 186,145 | NEW |
| CRBP | CORBUS PHARMACEUTICALS HOLDI | 0.30% | 1,737,287 | HELD |
| VERA | VERA THERAPEUTICS INC | 0.29% | 369,596 | HELD |
| ALMS | ALUMIS INC | 0.29% | 548,163 | HELD |
| EYPT | EYEPOINT INC | 0.28% | 1,069,147 | HELD |
| WAT | WATERS CORP /DE/ | 0.28% | 40,300 | NEW |
| MNPR | MONOPAR THERAPEUTICS INC | 0.27% | 157,423 | NEW |
| TVTX | Travere Therapeutics, Inc. | 0.27% | 253,000 | NEW |
| TSHA | Taysha Gene Therapies, Inc. | 0.25% | 2,000,000 | NEW |
| BIIB | BIOGEN INC. | 0.25% | 61,600 | HELD |
| RVMD | REVOLUTION MEDICINES INC | 0.24% | 70,500 | ADDED (+35.6%) |
| DNTH | Dianthus Therapeutics, Inc. /DE/ | 0.21% | 115,000 | NEW |
| SPRB | SPRUCE BIOSCIENCES INC | 0.20% | 200,000 | NEW |
| LFST | LifeStance Health Group, Inc. | 0.19% | 947,400 | ADDED (+89.5%) |
| ERAS | ERASCA INC | 0.17% | 495,900 | NEW |
| TARA | PROTARA THERAPEUTIC INC | 0.16% | 2,220,000 | NEW |
| KROS | KEROS THERAPEUTICS INC | 0.15% | 759,155 | HELD |
| JANX | JANUX THERAPEUTICS INC | 0.15% | 524,700 | TRIMMED (-46.7%) |
| TECX | TECTONIC THERAPEUTIC INC | 0.14% | 226,600 | HELD |
| ACET | ADICET BIO INC | 0.14% | 844,787 | TRIMMED (-17.8%) |
| PHVS | Pharvaris N.V. | 0.13% | 205,400 | HELD |
| ANRO | Alto Neuroscience, Inc. | 0.13% | 257,852 | ADDED (+53.9%) |
| ZNTL | Zentalis Pharmaceuticals, Inc. | 0.12% | 1,390,576 | NEW |
| DRUG | BRIGHT MINDS BIOSCIENCES INC | 0.12% | 93,000 | ADDED (+132.5%) |
| ALXO | ALX ONCOLOGY HOLDINGS INC | 0.11% | 2,866,256 | HELD |
| XLO | XILIO THERAPEUTICS INC | 0.11% | 592,300 | NEW |
| BCAX | BICARA THERAPEUTICS INC | 0.11% | 191,100 | TRIMMED (-71.4%) |
| IMA | IMAGENEBIO INC | 0.10% | 909,269 | ADDED (+140.2%) |
| PTGX | Protagonist Therapeutics, Inc | 0.10% | 42,100 | HELD |
| ALNY | ALNYLAM PHARMACEUTICALS, INC. | 0.09% | 17,000 | TRIMMED (-85.7%) |
| PALI | PALISADE BIO INC | 0.09% | 2,333,000 | HELD |
| PTCT | PTC THERAPEUTICS, INC. | 0.07% | 49,100 | HELD |
| AORT | ARTIVION, INC. | 0.07% | 175,000 | ADDED (+15.9%) |
| NMRA | NEUMORA THERAPEUTICS INC | 0.07% | 2,139,882 | NEW |
| ACAD | ACADIA PHARMACEUTICALS INC | 0.06% | 137,000 | NEW |
| AMLX | Amylyx Pharmaceuticals, Inc. | 0.06% | 183,400 | NEW |
| TYRA | TYRA BIOSCIENCES INC | 0.06% | 102,000 | NEW |
| RAPP | RAPPORT THERAPEUTICS INC | 0.06% | 76,616 | NEW |
| AGMB | AGOMAB THERAPEUTICS NV | 0.05% | 192,740 | NEW |
| TARS | TARSUS PHARMACEUTICALS INC | 0.04% | 35,581 | NEW |
| ACRS | ACLARIS THERAPEUTICS INC | 0.04% | 421,500 | NEW |
| CYTK | CYTOKINETICS INC | 0.04% | 25,800 | NEW |
| NSPR | INSPIREMD INC | 0.04% | 3,133,405 | HELD |
| OCUL | OCULAR THERAPEUTIX INC | 0.04% | 220,000 | NEW |
| EVMN | EVOMMUNE INC | 0.04% | 161,000 | NEW |
| BLTE | BELITE BIO, INC | 0.04% | 13,300 | NEW |
| OVID | OVID THERAPEUTICS INC | 0.04% | 747,000 | NEW |
| EPRX | EUPRAXIA PHARMACEUTICALS INC | 0.03% | 269,000 | NEW |
| TRAW | TRAWS PHARMA INC | 0.02% | 1,203,260 | ADDED (+98.7%) |
The weights above sum to 95.8% of the fund’s reported 13F value. Only positions matched to a U.S.-listed ticker are listed; the remainder sits in unmatched or non-equity positions in the filing.
Exited this quarter: ADCT, ALHC, AMGN, ASND, AVTX, BTSG, CARL, CCCC, CGEM, CMPS, DHR, GILD, HRTX, JBIO, MDXH, MYGN, PFE, RCEL, RCEL, REGN, VTGN.
Source: SEC Form 13F filing for the quarter ended Jun 30, 2026, filed Aug 14, 2026. CIK 0001055951. Change labels compare with the fund’s previous quarterly filing. 13F filings cover long positions only.
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