RA Capital Management

Superinvestor profile · Rank #37 by reported 13F value (2026 Q2 filers) · CIK 0001346824 · All profiles
Founded 2002Boston, Massachusetts, United StatesMulti-stage healthcare, biotechnology and planetary health investing across public and private marketsKey person: Peter Kolchinsky
Reported 13F value
$11.5B
Period 2026-06-30 · Filed 2026-08-14
Positions
84
Top 10 = 60.4% of value
Clone performance
Withheld
Price coverage too low — see note
Latest-quarter activity
17 new · 18 exited
10 increased · 10 decreased
Clone performance withheld for this manager. Only 66.5% of the latest filing's reported value sits inside our price history, and on average 52% of each historical segment's weight is unpriced as well; the rest is mostly non-U.S. listings and small-cap names we cannot price reliably. A clone computed from the priced minority would misrepresent the disclosed portfolio, so we do not publish one. The snapshot, holdings and filing history below are complete as reported. Evidence: filing-by-filing dossier (PDF) · Methodology (PDF)

Top holdings — 2026 Q2 filing

TickerCompanyWeightReported value
ASNDAscendis Pharma A/S23.83%$2.7B
PBLSParabilis Medicines Inc6.88%$792M
RYTMRhythm Pharmaceuticals Inc6.43%$740M
PCVXVaxcyte Inc5.80%$667M
SIONSionna Therapeutics Inc3.79%$436M
TYRATyra Biosciences Inc3.39%$390M
EWTXEdgewise Therapeutics Inc2.96%$341M
NAMSNewamsterdam Pharma Co Nv2.81%$324M
COAGHemab Therapeutics Holdings2.49%$287M
SEPNSepterna Inc2.04%$234M

As reported on the 2026-06-30 Form 13F (filed 2026-08-14). Full holdings and quarter changes: holdings page.

Filing history in this profile

Every clone input traces to one of these SEC filings. 66.5% of the latest filing's reported value is covered by our price history; the remainder is mostly non-U.S. listings, recent IPOs or delisted names and is excluded from the clone.

QuarterSEC accession no.FiledDisclosed CUSIPs
2026Q20001104659-26-0972512026-08-1484
2026Q10001104659-26-0626372026-05-1585
2025Q40001104659-26-0164822026-02-1771
2025Q30001104659-25-1124692025-11-1467
2025Q20001104659-25-0786912025-08-1463
2025Q10001104659-25-0495492025-05-1585
2024Q40001104659-25-0141812025-02-1489
2024Q30001104659-24-1190342024-11-1481
2024Q20001104659-24-0896292024-08-1478
2024Q10001104659-24-0630502024-05-171
2023Q40001104659-24-0239842024-02-1462
2023Q30001104659-23-1184522023-11-151
2023Q20001104659-23-0914052023-08-1454
2023Q10001104659-23-0607852023-05-1559
2022Q40001104659-23-0218472023-02-1470
2022Q30001104659-22-1186542022-11-1481
2022Q20001104659-22-0913312022-08-1588
2022Q10001104659-22-0613862022-05-1696
2021Q40001104659-22-0228072022-02-1497
2021Q30001104659-21-1392492021-11-1595
2021Q20001104659-21-1063862021-08-1692
2021Q10001104659-21-0681492021-05-1782
2020Q40001104659-21-0241612021-02-1682
2020Q30001104659-20-1258582020-11-1670
2020Q20001104659-20-0955622020-08-1457
2020Q10001104659-20-0626632020-05-1548
2019Q40001104659-20-0219282020-02-1434
2019Q30001104659-19-0642632019-11-1432
2019Q20001144204-19-0400932019-08-1425
2019Q10001144204-19-0266102019-05-1529
2018Q40001144204-19-0082352019-02-1425
2018Q30001144204-18-0599772018-11-1426
2018Q20001144204-18-0447122018-08-1427
2018Q10001144204-18-0288962018-05-1531
2017Q40001144204-18-0089632018-02-1427
2017Q30001144204-17-0590642017-11-1427
2017Q20001144204-17-0432122017-08-1422
2017Q10001144204-17-0275352017-05-1524
2016Q40001144204-17-0095692017-02-161
2016Q30001144204-16-1343252016-11-1430

Background (founded / HQ / style) source: https://en.wikipedia.org/wiki/RA_Capital_Management — Co-founded by Richard Aldrich and Peter Kolchinsky; Wikipedia infobox lists founded January 2002, while firm materials say officially formed / founded in 2004.