Reported value
$11.5B
2026 Q2 filing
| Ticker | Company | Weight | Shares | Change |
|---|---|---|---|---|
| ASND | Ascendis Pharma A/S | 23.83% | 10,281,496 | NEW |
| PBLS | PARABILIS MEDICINES INC | 6.88% | 28,933,371 | NEW |
| RYTM | RHYTHM PHARMACEUTICALS INC | 6.43% | 6,666,837 | HELD |
| PCVX | Vaxcyte, Inc. | 5.80% | 11,474,599 | HELD |
| SION | Sionna Therapeutics, Inc. | 3.79% | 9,905,045 | HELD |
| TYRA | TYRA BIOSCIENCES INC | 3.39% | 12,198,625 | HELD |
| EWTX | Edgewise Therapeutics, Inc. | 2.96% | 8,392,730 | TRIMMED (-19.5%) |
| NAMS | NewAmsterdam Pharma Co N.V. | 2.81% | 9,550,191 | HELD |
| COAG | HEMAB THERAPEUTICS HOLDINGS | 2.49% | 7,808,627 | NEW |
| SEPN | SEPTERNA INC | 2.04% | 6,995,858 | HELD |
| BCAX | BICARA THERAPEUTICS INC | 1.87% | 7,255,993 | HELD |
| MLYS | MINERALYS THERAPEUTICS INC | 1.80% | 7,692,750 | HELD |
| GHRS | GH Research PLC | 1.78% | 7,636,813 | TRIMMED (-0.5%) |
| IRON | DISC MEDICINE INC | 1.56% | 2,450,221 | HELD |
| SGP | SPYGLASS PHARMA INC | 1.55% | 8,021,117 | HELD |
| ARTV | Artiva Biotherapeutics, Inc. | 1.51% | 17,955,642 | ADDED (+82.2%) |
| JANX | JANUX THERAPEUTICS INC | 1.49% | 11,189,693 | HELD |
| TSHA | Taysha Gene Therapies, Inc. | 1.39% | 23,555,648 | HELD |
| BCRX | BIOCRYST PHARMACEUTICALS INC | 1.38% | 15,827,186 | HELD |
| WVE | Wave Life Sciences, Inc. | 1.36% | 26,975,505 | HELD |
| ABVX | Abivax S.A. | 1.31% | 1,132,557 | NEW |
| ORKA | Oruka Therapeutics, Inc. | 1.29% | 1,554,597 | NEW |
| CLYM | CLIMB BIO INC | 1.28% | 11,300,939 | HELD |
| SLDB | SOLID BIOSCIENCES INC | 1.04% | 12,036,126 | ADDED (+28.9%) |
| ZLAB | Zai Lab Ltd | 0.95% | 5,743,533 | ADDED (+0.6%) |
| SPRY | ARS Pharmaceuticals, Inc. | 0.76% | 10,860,977 | HELD |
| XNCR | XENCOR INC | 0.74% | 5,274,274 | ADDED (+7.7%) |
| JBIO | JADE BIOSCIENCES INC | 0.71% | 3,671,083 | HELD |
| NTLA | Intellia Therapeutics, Inc. | 0.67% | 4,526,926 | NEW |
| LBRX | LB PHARMACEUTICALS INC | 0.62% | 2,208,604 | HELD |
| DFTX | DEFINIUM THERAPEUTICS INC | 0.61% | 1,500,000 | NEW |
| ACRS | ACLARIS THERAPEUTICS INC | 0.58% | 12,723,026 | ADDED (+87.0%) |
| FDMT | 4D Molecular Therapeutics, Inc. | 0.58% | 5,049,779 | HELD |
| SANA | SANA BIOTECHNOLOGY INC | 0.57% | 18,750,000 | NEW |
| DMRA | Damora Therapeutics, Inc. | 0.54% | 2,399,702 | HELD |
| MNPR | MONOPAR THERAPEUTICS INC | 0.54% | 667,207 | HELD |
| ABOS | ACUMEN PHARMACEUTICALS INC | 0.49% | 20,992,669 | HELD |
| GERN | GERON CORP | 0.48% | 42,809,751 | TRIMMED (-32.9%) |
| RZLT | REZOLUTE INC | 0.43% | 9,445,039 | ADDED (+2.9%) |
| EVMN | EVOMMUNE INC | 0.40% | 3,494,638 | HELD |
| VOR | VOR BIOPHARMA INC | 0.38% | 2,402,095 | TRIMMED (-55.6%) |
| IPSC | CENTURY THERAPEUTICS INC | 0.38% | 17,754,430 | HELD |
| AKTS | Aktis Oncology, Inc. | 0.37% | 1,314,405 | TRIMMED (-12.6%) |
| BIOA | BIOAGE LABS INC | 0.36% | 1,671,648 | ADDED (+1.3%) |
| CCCC | C4 THERAPEUTICS INC | 0.32% | 8,000,000 | HELD |
| MIRM | Mirum Pharmaceuticals, Inc. | 0.32% | 318,554 | HELD |
| CAPR | CAPRICOR THERAPEUTICS INC | 0.32% | 1,507,844 | HELD |
| PEPG | PepGen Inc. | 0.31% | 20,064,545 | HELD |
| PRLD | PRELUDE THERAPEUTICS INC | 0.30% | 6,475,882 | NEW |
| NKTX | NKARTA INC | 0.27% | 10,805,129 | HELD |
| QTTB | Q32 BIO INC | 0.26% | 2,332,457 | NEW |
| AVR | ANTERIS TECHNOLOGIES GLOBAL | 0.26% | 3,000,000 | HELD |
| EDIT | EDITAS MEDICINE INC | 0.25% | 8,889,000 | NEW |
| OVID | OVID THERAPEUTICS INC | 0.25% | 10,500,968 | TRIMMED (-2.0%) |
| ASMB | ASSEMBLY BIOSCIENCES INC | 0.24% | 1,020,410 | HELD |
| ALXO | ALX ONCOLOGY HOLDINGS INC | 0.23% | 13,011,849 | HELD |
| BNTC | BENITEC BIOPHARMA INC | 0.22% | 1,850,000 | HELD |
| LENZ | LENZ THERAPEUTICS INC | 0.21% | 4,178,823 | HELD |
| LXEO | LEXEO THERAPEUTICS INC | 0.20% | 5,000,000 | HELD |
| ACRV | ACRIVON THERAPEUTICS INC | 0.19% | 12,229,396 | ADDED (+46.6%) |
| ALT | Altimmune, Inc. | 0.17% | 6,500,000 | NEW |
| KPTI | KARYOPHARM THERAPEUTICS INC | 0.16% | 1,917,354 | HELD |
| DRUG | BRIGHT MINDS BIOSCIENCES INC | 0.16% | 265,000 | HELD |
| AVTX | AVALO THERAPEUTICS INC | 0.16% | 1,000,000 | ADDED (+50.8%) |
| OKUR | ONKURE THERAPEUTICS INC-A | 0.16% | 3,998,333 | HELD |
| FTH | FAETH THERAPEUTICS INC | 0.16% | 722,020 | NEW |
| AURA | AURA BIOSCIENCES INC | 0.15% | 2,500,000 | NEW |
| SABS | SAB BIOTHERAPEUTICS INC | 0.15% | 4,401,500 | HELD |
| SPTX | SEAPORT THERAPEUTICS INC | 0.13% | 700,000 | NEW |
| PALI | PALISADE BIO INC | 0.13% | 7,124,116 | HELD |
| HLXC | Helix Acquisition Corp. III | 0.12% | 1,250,000 | HELD |
| WAY | WAYSTAR HOLDING CORP | 0.09% | 529,400 | HELD |
| EQ | EQUILLIUM INC | 0.09% | 3,096,336 | HELD |
| MGNX | MACROGENICS INC | 0.07% | 1,864,176 | HELD |
| ACET | ADICET BIO INC | 0.07% | 932,624 | TRIMMED (-21.1%) |
| CRVS | CORVUS PHARMACEUTICALS INC | 0.06% | 450,000 | HELD |
| RANI | RANI THERAPEUTICS HOLDINGS-A | 0.06% | 8,500,000 | HELD |
| JATT | JATT II Acquisition Corp. | 0.05% | 500,000 | NEW |
| AMAN | Amanat Acquisition Corp. | 0.03% | 375,000 | NEW |
| HOWL | WEREWOLF THERAPEUTICS INC | 0.01% | 2,387,744 | TRIMMED (-64.3%) |
| PTN | PALATIN TECHNOLOGIES INC | 0.01% | 62,124 | TRIMMED (-11.3%) |
The weights above sum to 98.5% of the fund’s reported 13F value. Only positions matched to a U.S.-listed ticker are listed; the remainder sits in unmatched or non-equity positions in the filing.
Exited this quarter: ASND, CTNM, DNTH, DSGN, FULC, GRAL, HNGE, INSP, MPLT, OLMA, PRAX, RLMD, RNA, SRPT, STRO, SYRE, TVTX, WGS.
Source: SEC Form 13F filing for the quarter ended Jun 30, 2026, filed Aug 14, 2026. CIK 0001346824. Change labels compare with the fund’s previous quarterly filing. 13F filings cover long positions only.
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